Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1745 (LINC01745)

Target
LINC01745
Molecular classification
Long non-coding RNA, Long intergenic non-coding RNA
01

Overview

Long intergenic non-protein coding RNA 1745 (LINC01745) is a member of the long non-coding RNA (lncRNA) family, specifically a "long intergenic non-coding RNA." These RNAs are transcribed from genomic regions that do not overlap protein-coding genes and are typically longer than 200 nucleotides[5][1][6]. LINC01745 is not known to encode a protein. While the specific functional significance of LINC01745 has not been characterized in the literature, lincRNAs in general are recognized for their diverse roles in regulating transcription, remodeling chromatin, and influencing nuclear architecture and gene expression[6][7]. Although lncRNAs as a class are increasingly recognized as potential regulators, disease modifiers, and in some cases biomarkers, no evidence currently links LINC01745 specifically to a disease or therapeutic intervention.

Other names
LINC01745ENSG00000225919 (Ensembl)
02

Biological functions

Transcriptional regulationChromatin remodelingModulation of gene expressionPotential fine-tuning of neighboring gene expression
03

Disease associations

No direct disease linkage identified for LINC01745; lincRNAs in general are implicated in cancer, cardiovascular disease, and toxicology.

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