Long intergenic non-protein coding RNA 1753 (LINC01753)

Long intergenic non-protein coding RNA 1753 (LINC01753) is a lincRNA—a long non-coding RNA transcript located in the intergenic regions of the genome, meaning it does not overlap with protein-coding genes[1][3]. LincRNAs play regulatory roles in the cell, particularly in modulating gene expression at both transcriptional and post-transcriptional levels, and often function as molecular sponges for microRNAs[5]. Aberrant expression of lincRNAs, including those similar to LINC01753, has been implicated in cancer pathogenesis, contributing to deregulation of signaling pathways, promotion of cell proliferation, inhibition of apoptosis, and oncogenic transformation[5]. However, LINC01753 itself is not a receptor, enzyme, transporter, nor is it currently recognized as a direct therapeutic target, and there are no known drugs targeting it specifically[1][3]. It remains a subject of study for its potential as a cancer biomarker or therapeutic target in the future.

Other names

LINC01753