Long intergenic non-protein coding RNA 1761 (LINC01761)

Long intergenic non-protein coding RNA 1761 (LINC01761) is a human long non-coding RNA (lncRNA) gene located on chromosome 1 (1q21.3, coordinates: 95,474,737-95,479,356, forward strand)[5][1][8]. It is transcribed but does not encode a protein and is annotated as a member of the lncRNA gene class, specifically a long intergenic non-coding RNA—an RNA longer than 200 nucleotides that lies between protein-coding genes and does not overlap any coding regions[5][1][8]. LINC01761 is listed in curated genomics databases such as Ensembl, HGNC (Accession HGNC:52551), BioGPS, and GeneCards, but its biological function, mechanism of action, patterns of expression, and connections to human disease remain poorly characterized and are currently unknown in the biomedical literature[1][5][8]. No credible evidence currently supports its status as a therapeutic target and no drugs are known to interact with this lncRNA. Genome-wide association studies (GWAS) have mapped some intergenic variants to this locus, potentially implicating it as a candidate gene in genetic association studies, but no direct clinical or mechanistic role has been established to date[3][7].

Other names

LINC01761