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Target intelligence / Profile preview
Long intergenic non-protein coding RNA 1770 (LINC01770)
- Target
- LINC01770
- Molecular classification
- Long non-coding RNA (lncRNA), Bidirectional promoter lncRNA
01
Overview
Long intergenic non-protein coding RNA 1770 (LINC01770) is a human long non-coding RNA gene located on chromosome 1 (chr1:1428122-1434573, minus strand). It is transcribed as multiple RNA isoforms, classed as a bidirectional promoter lncRNA. While lncRNAs often play roles in gene regulation, cell proliferation, apoptosis, and cancer biology, no characterized molecular functions, disease links, or drug interactions are definitively reported for LINC01770 in current reference sources. Unofficial aliases such as "RRFERV, radiation-resistant but ferroptosis vulnerable" are not established in the genomic or biomedical literature and should be considered unvalidated or potentially erroneous nomenclature.
- Other names
- LINC01770Long intergenic non-protein coding RNA 1770
02
Mechanism of action
None reported
03
Biological functions
No experimentally validated or literature-supported biological functions are described for LINC01770 itselfIt may play a regulatory role via RNA-based mechanisms typical for lncRNAs (e.g., chromatin remodeling, modulation of transcription), but specifics remain undetermined.
04
Disease associations
No established or specific disease association is described for LINC01770 in curated databases or literatureGeneral lncRNA involvement in cancer and other diseases is documented for other lncRNAs, but there is no information specific to LINC01770.
05
Safety considerations
None reportedNo clinical or preclinical safety data related to LINC01770 exist.
06
Biomarkers
None reportedLINC01770 has not been validated as a biomarker for disease state or therapeutic response.
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