Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1786 (LINC01786)

Target
LINC01786
Molecular classification
Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01

Overview

Long intergenic non-protein coding RNA 1786 (LINC01786) is a long non-coding RNA (lncRNA) transcript classified as a long intergenic non-coding RNA (lincRNA). It does not encode a protein but may regulate gene expression by interacting with chromatin, transcription factors, or RNA-binding proteins. LINC01786 is differentially expressed in subtypes of kidney and prostate cancer, suggesting a role in tumor biology. While specific functional and drug interaction data for this lincRNA are limited, lincRNAs as a class are known to influence chromatin structure, transcription regulation, and cell-type specific gene network modulation[1][3][5]. LINC01786 is not recognized as a classical pharmacological target such as a receptor, enzyme, or transporter, and no approved therapies are directed specifically at it[1][3]. Its upregulation in certain cancers suggests it could serve as a disease biomarker or a potential investigational target, but there is no current evidence of direct drug-targeting[3].

Other names
RP5-902P8.1001p36.33LINC01786[3]
02

Biological functions

Regulation of gene expressionChromatin remodeling (inferred from lincRNA family)RNA binding protein interaction (specifically with SRRM2 in cancer)Potential role as enhancer RNA or recruitment of transcription factors (general lincRNA function)
03

Disease associations

Cancer (notably upregulated in kidney renal papillary cell carcinoma [KIRP] and prostate adenocarcinoma [PRAD])
04

Biomarkers

Differential expression in several cancers, including KIRP and PRAD (potential biomarker for diagnosis or prognosis)

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