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Long intergenic non-protein coding RNA 1809 (LINC01809)
- Target
- LINC01809
- Molecular classification
- Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01
Overview
Long intergenic non-protein coding RNA 1809 (LINC01809) is a non-coding RNA gene producing a long intergenic non-coding RNA (lincRNA), which does not encode a protein and does not overlap annotated coding genes[1][3][7]. LincRNAs such as LINC01809 generally act as regulatory molecules within the cell, influencing gene expression by acting on chromatin structure, stabilizing RNA, or modulating transcription[3][5][7]. LINC01809 has been identified as being differentially expressed in cancer, particularly lung cancer, and may serve as a promising non-invasive biomarker for cancer detection and diagnosis, especially via blood-based assays[2]. There is no evidence it is a receptor, enzyme, transporter, or a conventional drug target, but rather a regulatory RNA with emerging interest in cancer biomarker development[2][3][7].
- Other names
- LINC01809
02
Biological functions
Chromatin remodelingGenome architecture modulationRNA stabilizationRegulation of gene transcription and expression, sometimes in a tissue- or context-specific manner
03
Disease associations
Cancer (notably, several lincRNAs including LINC01809 were identified by unbiased transcriptomic biomarker screens as being differentially expressed in cancer, particularly lung cancer)
04
Biomarkers
Potential biomarker for lung cancer diagnosis and patient stratification
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