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Long intergenic non-protein coding RNA 1843 (LINC01843)
- Target
- LINC01843
- Molecular classification
- Long noncoding RNA (lncRNA), Non-protein coding RNA, Regulatory RNA, Other
01
Overview
Long intergenic non-protein coding RNA 1843 (LINC01843) is a human long noncoding RNA gene located at chromosome 5q31, affiliated with the lncRNA class and characterized by its lack of protein-coding potential. Clinical studies have recognized LINC01843 as a methylation-related lncRNA associated with disease prognosis and molecular risk signatures in lung adenocarcinoma. Pathway analysis indicates enrichment in cancer-related mechanisms including epithelial-mesenchymal transition (EMT), hypoxia, stemness, and cell proliferation for the lncRNA cohort including LINC01843. There are currently no established drugs or direct pharmacological modulators for this molecule, and specific functional mechanisms and molecular interactors remain to be defined through experimental research. The gene is listed in major databases such as GeneCards, HGNC, and EBI GWAS, supporting its nomenclature as LINC01843.
- Other names
- LINC01843long intergenic non-protein coding RNA 1843lnc-APUE
02
Mechanism of action
Null (no drugs directly targeting LINC01843; inferred mechanisms may involve modulation of cell proliferation or methylation status)
03
Biological functions
Cell proliferation regulationEpigenetic modulationOther
04
Disease associations
CancerOther
05
Biomarkers
Prognostic biomarker in lung adenocarcinoma
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