Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1922 (LINC01922)

Target
LINC01922
Molecular classification
Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01

Overview

LINC01922 (Long intergenic non-protein coding RNA 1922) is a human gene encoding a long intergenic non-coding RNA (commonly categorized as a lincRNA)[1][3]. These molecules are transcribed RNA sequences longer than 200 nucleotides that do not overlap protein-coding genes and are generally thought not to code for proteins[1][5][7]. lincRNAs, including LINC01922, participate in a diversity of regulatory functions: they can modify chromatin, regulate genome architecture, stabilize and modulate other RNAs, act as molecular scaffolds for proteins, and fine-tune gene expression, often with marked tissue specificity[5][7]. Many lincRNAs have roles in the regulation of transcription and can influence nearby (cis) or distant (trans) gene targets through sequence-dependent or sequence-independent mechanisms[5][7]. A subset of lincRNAs has been implicated in human disease, but there is currently no specific disease association or direct therapeutic relevance known for LINC01922 itself, nor any drugs or biomarkers linked to its activity[1][3][5].

Other names
LINC01922
02

Biological functions

Chromatin remodelingGenome architecture regulationRNA stabilizationTranscription regulation (including enhancer activity)Scaffolding/modulating protein interactionsFine-tuning expression of neighboring genes
03

Disease associations

Other (While lincRNAs overall are implicated in various diseases, including cancer, there is no direct disease association currently confirmed for LINC01922 specifically)

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