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Long intergenic non-protein coding RNA 1998 (LINC01998) is a member of the long intergenic non-coding RNA (lincRNA) family. LincRNAs are autonomously transcribed non-coding RNAs longer than 200 nucleotides that do not overlap protein-coding genes. While thousands of lincRNAs have been annotated in the human genome, only a subset has been functionally characterized. LincRNAs typically regulate gene expression, influence chromatin structure, and participate in diverse regulatory processes via interactions with DNA, RNA, and proteins. Despite the overall functional significance of lincRNAs, most—including LINC01998—have not yet had their specific biological or disease-related roles elucidated, nor are they actionable therapeutic targets or validated biomarkers at present[1][2][3][5].
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