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Target intelligence / Profile preview
Long intergenic non-protein coding RNA 2004 (LINC02004)
- Target
- LINC02004
- Molecular classification
- Long intergenic non-coding RNA (lincRNA), Other (non-protein coding RNA)
01
Overview
LINC02004 is a human long intergenic non-protein coding RNA, representing a member of the lincRNA family. LINC02004 does not encode a protein but is transcribed from a distinct intergenic locus in the human genome and classified among lncRNAs involved in gene regulation. Published data indicate LINC02004 is included in a panel of ferroptosis-related long non-coding RNAs used to construct prognostic risk signatures for cancer, particularly pancreatic adenocarcinoma. There is no specific evidence for its individual function, interacting molecules, or therapeutic targeting; functional roles are presumptive, based on general knowledge of lincRNA biology and regulation in cancer pathways.
02
Mechanism of action
None found
03
Biological functions
Regulation of ferroptosis in cancer cells (inferred from participation in a published prognostic signature)Potential regulation of gene expression and epigenetic pathways (general lincRNA function)
04
Disease associations
Cancer (listed in a multi-lncRNA signature for cancer prognosis and ferroptosis pathways)Other (possible relevance in cell cycle or cell proliferation inferred from general lincRNA literature)
05
Biomarkers
Candidate as a biomarker for cancer prognosis (part of multigene risk signatures for cancer survival)
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