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Long intergenic non-protein coding RNA 2041 (LINC02041)

Target
LINC02041
Molecular classification
Long intergenic non-coding RNA (lincRNA), Long non-coding RNA (lncRNA), Other
01

Overview

Long intergenic non-protein coding RNA 2041 (LINC02041) is a human long non-coding RNA gene, classified specifically as a long intergenic non-coding RNA (lincRNA)[1][3]. LINC02041 transcripts are not believed to encode proteins but may regulate gene expression and chromatin structure[5][7]. Clinically, LINC02041 is significantly upregulated in various tumors, especially pancreatic adenocarcinoma, and its high expression correlates with a higher hazard ratio and poorer 5-year survival in such patients, indicating its value as a prognostic biomarker[3]. It is also part of lncRNA-based models for predicting overall survival in head and neck squamous cell carcinoma and shows diagnostic performance in colorectal cancer[6][3]. No direct therapeutic targeting, approved drugs, or well-characterized interacting partners are documented; its primary significance is currently as a biomarker and potential mediator of tumor biology, rather than as a therapeutic target or known receptor, enzyme, or transporter[3][6][5].

Other names
RP11-567G11.1linc02041
02

Biological functions

Likely involved in regulation of gene expressionPotential as a prognostic biomarkerMay influence chromatin or RNA metabolism (general lincRNA functions)
03

Disease associations

Cancer (implicated in pancreatic adenocarcinoma, head and neck squamous cell carcinoma, colorectal cancer)Other (possible involvement in other tumor-related regulation)
04

Biomarkers

Upregulated LINC02041 is a prognostic marker for poor survival in pancreatic adenocarcinoma and other cancers; has potential diagnostic value in colorectal cancer

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