Target intelligence / Profile preview

Long intergenic non-protein coding RNA 2059 (LINC02059)

Target
LINC02059
Molecular classification
Long non-coding RNA (lncRNA), Non-protein coding RNA, Other
01

Overview

Long intergenic non-protein coding RNA 2059 (LINC02059) is a non-protein coding RNA molecule classified as a long non-coding RNA (lncRNA); these RNAs are greater than 200 nucleotides in length and do not encode proteins[1][3][5]. LINC02059 is annotated in gene databases such as NCBI Gene (Gene ID: 100505878) and Ensembl (ENSG00000250544)[1][5]. While comprehensive functional characterization of LINC02059 is lacking, high-throughput studies have identified certain lncRNAs, including LINC02059, as being differentially expressed in cancer versus normal tissue, suggesting potential use as a biomarker for cancer, particularly lung cancer, where lncRNA expression patterns can aid in distinguishing tumors from normal samples[2]. There is currently no evidence that LINC02059 functions as a receptor, enzyme, transporter, or other direct therapeutic target. No drugs are known to act through LINC02059, and its specific molecular mechanisms or safety implications as a therapeutic target have not been established[1][3][5].

Other names
CTC-493L21.1LINC02059
02

Biological functions

Regulation of gene expression (by lncRNA class association)Other
03

Disease associations

Cancer (potential biomarker role indicated in some studies)
04

Biomarkers

Potential biomarker for lung cancer (diagnostic signature as part of lncRNA panels)[2]

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