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Long intergenic non-protein coding RNA 2132 (LINC02132)

Target
LINC02132
Molecular classification
Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01

Overview

Long intergenic non-protein coding RNA 2132 (LINC02132) is a member of the long non-coding RNA (lncRNA) class, specifically classified as a long intergenic non-coding RNA (lincRNA)[3]. LINC02132 does not encode a protein and functions primarily at the RNA level. Recent studies indicate that upregulation of LINC02132 increases intracellular reactive oxygen species (ROS) levels in melanoma cells, suppressing their proliferation, migration, and invasion while promoting apoptosis[2]. These findings suggest LINC02132 may function as a tumor suppressor and as a prognostic biomarker for melanoma; however, it is not established as a direct therapeutic target or receptor, enzyme, transporter, or similar molecule[2][3]. No drugs are currently known to directly interact with LINC02132.

Other names
LINC02132
02

Biological functions

Regulation of oxidative stress responseModulation of cell proliferationModulation of cell migrationModulation of cell invasionRegulation of apoptosis
03

Disease associations

CancerSpecifically implicated as tumor suppressor in melanoma
04

Biomarkers

Prognostic biomarker for melanoma (prognosis related oxidative stress-associated lncRNA)

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