Long intergenic non-protein coding RNA 2145 (LINC02145)

Long intergenic non-protein coding RNA 2145 (LINC02145) is a human long intergenic non-coding RNA (lincRNA), transcribed from non-coding regions of the genome that do not overlap protein-coding genes. LINC02145 is part of a class of non-coding RNAs longer than 200 nucleotides, generally involved in the regulation of gene expression, chromatin structure, and transcriptional activity but lacks protein-coding potential. While the specific biological roles of LINC02145 remain uncharacterized, lincRNAs as a group can function in chromatin remodeling, modulating mRNA stability, and regulation of transcription, often with tissue-specific expression patterns. LINC02145 and similar lncRNAs have been proposed as potential biomarkers for cancer detection and classification, but there is currently no evidence supporting its role as a direct therapeutic target or interacting with drugs.\n\nLINC02145 is annotated and indexed in gene databases as a long non-coding RNA, specifically “long intergenic non-protein coding RNA 2145,” with symbol LINC02145. There are no references supporting its function as an enzyme, transporter, receptor, or any other classical druggable target, so it is not considered a therapeutic target at this time. It has been included in lncRNA panels explored for their potential as diagnostic biomarkers and machine learning classifiers in cancer, notably in lung cancer datasets. No specific data exist for disease mechanisms, direct drug interactions, or safety profiles. Its relevance currently remains in the realm of *biomarker discovery* rather than direct modulation by drugs or as a target for therapy.

Other names

FLJ33360CTCCTD-2324F15.2LINC02145