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Long intergenic non-protein coding RNA 2161 (LINC02161) is a gene that produces a long non-coding RNA transcript in humans[6][1]. LINC02161 belongs to the long intergenic non-coding RNA (lincRNA) family, which comprises transcripts longer than 200 nucleotides that do not overlap coding genes. While thousands of lincRNAs have been identified, only a few have well-characterized functions. Generally, lincRNAs are known to regulate gene expression in a variety of ways, including chromatin remodeling, modulation of transcription, and regulation of nuclear domain architecture. Some lincRNAs possess enhancer-like activities, may influence gene expression in *cis* (nearby genes), and can have highly tissue-specific expression[3][5]. However, the specific functions and disease associations of LINC02161 have not been well characterized according to current genomic databases[1][6].
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