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Long intergenic non-protein coding RNA 2235 (LINC02235)
- Target
- LINC02235
- Molecular classification
- Long non-coding RNA (lncRNA), long intergenic non-coding RNA (lincRNA)
01
Overview
Long intergenic non-protein coding RNA 2235 (LINC02235) is a non-coding RNA gene that produces a lincRNA, defined as an autonomously transcribed RNA longer than 200 nucleotides that does not overlap with protein-coding genes. LINC02235 belongs to a large family of lincRNAs, whose members generally remodel chromatin, regulate transcription, and serve as scaffolds for protein complexes, often affecting gene expression and cellular phenotype with notable tissue specificity. Although numerous lincRNAs have well-characterized and diverse regulatory functions in development and disease, there is currently no evidence of direct functional, disease, or therapeutic association documented for LINC02235 itself
- Other names
- RP11-354A14.1LINC02235
02
Mechanism of action
Not applicable; there are no drugs targeting this molecule.
03
Biological functions
Regulation of chromatin structureTranscriptional regulationPotential enhancer-associated activityFine-tuning expression of neighboring genes with tissue specificityRNA stabilizationScaffolding and modulating protein and RNA interactions
04
Disease associations
No specific disease role is documented for LINC02235 itself. Generally, lincRNAs are implicated in regulatory functions in cancer, development, and other diseases, but direct associations for LINC02235 are unknown
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