Long intergenic non-protein coding RNA 2241 (LINC02241)

Long intergenic non-protein coding RNA 2241 (LINC02241) is a human long intergenic non-coding RNA (lincRNA) gene. LINC02241 does not code for a protein but has been found to be expressed in various human tissues. Like other lincRNAs, LINC02241 is believed to regulate gene expression through mechanisms such as chromatin remodeling, recruitment of transcription factors, interaction with RNA-binding proteins, and modulation of alternative splicing. Notably, LINC02241 has been associated with cancer, showing expression in hepatocellular carcinoma samples and an association with poor prognosis in colorectal cancer. Recent research suggests LINC02241 may be a source of tumor-specific antigens due to its non-canonical translation into HLA-bound peptides in cancer cells, making it of interest as a potential biomarker and a target for cancer immunotherapy research, despite not being a classic therapeutic target like a receptor, enzyme, or transporter[1][2][3].

Other names

RP11-774D14.105p14.3LINC02241