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Long intergenic non-protein coding RNA 2245 (LINC02245)

Target: LINC02245
Molecular classification: Long non-coding RNA (lncRNA class), Other (not a protein-coding gene, not a receptor)

Overview

Long intergenic non-protein coding RNA 2245 (LINC02245) is an lncRNA gene located on human chromosome 2 (GRCh38: 64,901,840-65,056,233, reverse strand). It produces multiple transcript variants, but none are protein-encoding; all function as lncRNAs. Common aliases include lnc-SERTAD2-3 and AC007386.2. There is no demonstrated biological function, disease association, drug interaction, or mechanism of action for LINC02245 at present. It remains a non-protein-coding gene with unknown biological significance and is not considered a therapeutic target.

Other names: lnc-SERTAD2-3AC007386.2

Biological functions

There is currently insufficient published evidence for specific biological functions of LINC02245. As an lncRNA, potential functions may include regulation of gene expression, epigenetic modification, or modulation of other non-coding RNAs, but specific roles for LINC02245 have not been characterized in the available sources.

Disease associations

There is no direct evidence reported of LINC02245 involvement in any diseases such as cancer, inflammation, neurodegenerative, cardiovascular, or infection-associated disorders. However, many lncRNAs are increasingly studied for roles in cancer and other conditions; roles for LINC02245 remain to be determined.

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