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Long intergenic non-protein coding RNA 2297 (LINC02297) is a type of long intergenic non-coding RNA (lincRNA), meaning it is a transcript longer than 200 nucleotides that does not overlap with protein-coding genes[5][1][3]. LINC02297 is cataloged as a non-protein-coding gene and is part of the broader family of lincRNAs, which constitute more than half of the annotated long non-coding RNA transcripts in the human genome[3][5]. These RNAs have diverse regulatory roles, including fine-tuning the expression of neighboring genes, modulating chromatin structure, stabilizing other RNAs, and acting as enhancers in certain contexts[3]. While thousands of lincRNAs—including LINC02297—have been annotated, only a small fraction have been directly linked to defined cellular functions or human diseases. At present, there is no specific evidence that LINC02297 serves as a therapeutic target, interacts directly with approved drugs, or functions as a biomarker or safety concern in clinical practice[1][5].
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