Target intelligence / Profile preview

Long intergenic non-protein coding RNA 2395 (LINC02395)

Target
LINC02395
Molecular classification
Long non-coding RNA, Long intergenic non-protein coding RNA
01

Overview

Long intergenic non-protein coding RNA 2395 (LINC02395) is a human long intergenic non-coding RNA (lincRNA), defined as a non-coding RNA longer than 200 nucleotides that is transcribed from intergenic regions of the genome and does not overlap any protein-coding genes[1][3][7]. LincRNAs, including LINC02395, are part of the broader lncRNA class and are thought to play important regulatory roles, such as chromatin and genome remodeling, transcriptional modulation, RNA stabilization, and scaffolding of regulatory protein complexes[1][3]. While some lincRNAs have established roles in development and disease, there is currently no disease association or drug targeting specifically described for LINC02395. This molecule chiefly represents a structural and regulatory RNA without protein-coding potential, and remains a subject of functional genomics research rather than a therapeutic target[1][3][7].

Other names
LINC02395
02

Mechanism of action

Not applicable (no drugs known to target this molecule)

03

Biological functions

Chromatin remodelingRegulation of genome architectureRNA stabilizationTranscription regulationPotential enhancer-associated activityScaffolding and modulation of protein activityFine-tuning expression of neighboring genes
04

Disease associations

Other (while many lincRNAs/lncRNAs have been linked to diseases including cancer, there is no direct evidence currently linking LINC02395 itself to human disease)

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