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Long intergenic non-protein coding RNA 2521 (LINC02521) is a human lincRNA gene, defined as an autonomously transcribed non-coding RNA longer than 200 nucleotides that does not overlap a coding gene[1][3][5][7]. LincRNAs, including LINC02521, regulate gene expression through diverse mechanisms such as chromatin remodeling, RNA-protein scaffolding, stabilization of RNAs, and enhancer-like activity[5][7]. Unlike protein-coding genes, lincRNAs predominantly modulate cellular function by influencing the expression of other genes and by forming ribonucleoprotein complexes, often in a sequence- or structure-dependent manner. No evidence currently supports LINC02521 as a druggable target or biomarker in human disease[1][3].
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