Long intergenic non-protein coding RNA 2525 (LINC02525)

LINC02525 (Long intergenic non-protein coding RNA 2525) is a long non-coding RNA gene located on chromosome 6p25.2. It is highly expressed in certain cancers, notably neuroblastoma and glioma. Experimental studies demonstrate that LINC02525 can enhance tumor cell migration and invasion, influence cell proliferation, and regulate apoptosis, likely through interaction with cellular proteins such as ribosomal protein RPL35. LINC02525 and related lncRNAs are emerging as important players in cancer progression and are under exploration as potential therapeutic targets and biomarkers in oncology. No classical small molecule or biologic drugs currently target LINC02525 directly, but ongoing research may identify targeted therapies or RNA-based interventions in the future.

Other names

TP53LC14lncNB1RP1-40E16.9lncRNA highly expressed in neuroblastoma 1lincNB1

Not applicable for classical small molecules; experimental evidence suggests it acts by binding/interacting with specific proteins such as RPL35, influencing gene expression and tumor cell behaviors