Target intelligence / Profile preview

Long intergenic non-protein coding RNA 2563 (LINC02563)

Target
LINC02563
Molecular classification
Other (Long non-coding RNA)
01

Overview

Long intergenic non-protein coding RNA 2563 (LINC02563) is a human long non-coding RNA (lncRNA) gene, officially named and approved by the HUGO Gene Nomenclature Committee (HGNC ID: HGNC:52923)[3][5][7]. Also known by aliases such as CRAT40 and cervical cancer-associated transcript 40, LINC02563 does not encode a protein but is believed to regulate gene expression at the transcriptional and/or post-transcriptional levels. Current research suggests a role in the progression of cancer, most notably cervical cancer, where its dysregulated expression has been associated with disease.[2][5][7] Evidence points to altered LINC02563 expression as a candidate biomarker for cervical cancer diagnosis or progression risk, but there are currently no known drug interactions, approved therapies, or established mechanisms of therapeutic targeting. LINC02563 is not classified as a receptor, enzyme, transporter, or classical drug target, but as a long non-coding RNA involved in cancer biology[1][3][5][7][8].

Other names
CRAT40cervical cancer-associated transcript 40CTD-2535L24.3
02

Mechanism of action

Not a direct therapeutic target; no approved or experimental drugs with defined mechanisms of action reported

03

Biological functions

Regulation of gene expressionPotential roles in cell proliferation and cell cyclePossible involvement in cellular differentiation processes
04

Disease associations

Cancerwith strongest evidence in cervical cancer
05

Biomarkers

Candidate biomarker for cervical cancer progression risk

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