Target intelligence / Profile preview

Long intergenic non-protein coding RNA 2594 (LINC02594)

Target
LINC02594
Molecular classification
Long non-coding RNA, Long intergenic non-coding RNA (lincRNA)
01

Overview

Long intergenic non-protein coding RNA 2594 (LINC02594) is a member of the long non-coding RNA family, specifically classified as a long intergenic non-coding RNA (lincRNA). These are RNA molecules transcribed from genomic regions that do not overlap with known protein-coding genes and do not code for proteins themselves[1][3][5]. LINC02594 is also referred to as CTC-501O10.1, AC100830.4, and RP11-210K20.5[9]. While its specific biological functions have not been comprehensively defined, lincRNAs are generally involved in the regulation of gene expression—often by acting as molecular sponges for microRNAs or influencing chromatin structure and mRNA stability[3][5]. An upregulation of LINC02594 and its aliases has been reported in the plasma of gastric cancer patients, suggesting a potential role as a biomarker in this context[9]. There is currently insufficient evidence to classify LINC02594 as a direct therapeutic target or assign it specific interacting drugs or mechanisms of action.

Other names
CTC-501O10.1LINC02594AC100830.4RP11-210K20.5
02

Biological functions

Regulation of gene expressionModulation of microRNA availability (e.g., as a molecular sponge)Potential roles in cell proliferation and cell cycle (general for lincRNAs)
03

Disease associations

Cancer (upregulation noted in gastric cancer)
04

Biomarkers

Possible biomarker for gastric cancer (upregulation in plasma)

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