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Target intelligence / Profile preview
Long intergenic non-protein coding RNA 2652 (LINC02652)
- Target
- LINC02652
- Molecular classification
- Long non-coding RNA (lncRNA), Other
01
Overview
Long intergenic non-protein coding RNA 2652 (LINC02652) is a long non-coding RNA gene located on chromosome 10p12.1. Like other lncRNAs, it does not encode a protein but may exert regulatory effects on gene expression at different levels, though its specific functions are not well characterized. Genetic variants within LINC02652 have been linked to quantitative blood cell traits such as granulocyte, basophil, and eosinophil counts. There is no wide consensus implicating LINC02652 in major disease roles or as a drug target, and functional characterization remains limited.
- Other names
- LINC02652long intergenic non-protein coding RNA 2652
02
Mechanism of action
None established for drugs (not a pharmacological target)
03
Biological functions
Possible involvement in regulation of gene expression (by analogy with other lncRNAs)Association with blood cell trait variation (granulocyte, basophil, eosinophil counts via genetic variants)Other (due to limited characterization)
04
Disease associations
Other (there are currently no published associations with major disease processes such as cancer, inflammation, etc.; only correlation with blood cell counts by GWAS)
05
Biomarkers
Genetic variants within LINC02652 (such as rs2998286, rs2807743) are associated with blood cell counts and may have potential as biomarkers in hematological studies
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