Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Long intergenic non-protein coding RNA 2908 (LINC02908)
- Target
- LINC02908
- Molecular classification
- Other (classified as long non-coding RNA or lncRNA), Long non-coding RNA
01
Overview
Long intergenic non-protein coding RNA 2908 (LINC02908) is a human long non-coding RNA gene associated with the regulation of cell growth and chemotherapy resistance in cancers such as pancreatic ductal adenocarcinoma and leukemia. It is classified as a long non-coding RNA rather than a protein-coding gene, and acts as a regulatory molecule modulating microRNA activity and downstream gene expression. Although implicated in cancer biology, it is not a classical drug target such as a receptor or enzyme, but its expression and activity are of interest for cancer research and possible future interventions.
- Other names
- C9orf139FLJ36268FLJ42909uncharacterized protein C9orf139Putative uncharacterized protein LINC02908
02
Mechanism of action
Regulates tumor biology by sponging microRNAs, e.g., miR-24-3p in acute myeloid leukemia, miR-663a in pancreatic cancer, impacting gene expression and cell growth
03
Biological functions
Regulation of cell proliferation in cancerMediating chemotherapy resistancePossibly regulating tumor growth via competing endogenous RNA mechanisms (ceRNA), specifically by sponging microRNAs under some aliases (see C9orf139 in leukemia)
04
Disease associations
Cancer (Pancreatic ductal adenocarcinoma, acute myeloid leukemia)Chemotherapy resistance in chronic myeloid leukemia
Beyond the preview
Go deeper on Long intergenic non-protein coding RNA 2908 (LINC02908).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Long intergenic non-protein coding RNA 2908 (LINC02908).