Target intelligence / Profile preview

Long intergenic non-protein coding RNA 2985 (LINC02985)

Target
LINC02985
Molecular classification
Long non-coding RNA (lncRNA), Other (non-coding RNA family)
01

Overview

Long intergenic non-protein coding RNA 2985 (LINC02985) is a member of the long non-coding RNA (lncRNA) family, located in an intergenic region of the human genome[1][5]. LINC02985 does not encode a protein and functions primarily by regulating the expression of other genes, often at the level of chromatin structure, RNA stability, or by acting as molecular scaffolds[1][2]. Recent research suggests that LINC02985, alongside other lncRNAs, may be involved in modulating the immune microenvironment and cancer progression, serving as part of multivariate risk models for patient prognosis, especially in gastric cancer[2]. However, the precise biological functions and molecular mechanisms of LINC02985 require further investigation. As of now, it is not a classical drug target, nor are there drugs that directly modulate its activity.

Other names
AC156455.1LINC02985
02

Biological functions

Regulation of gene expressionPotential involvement in immune response regulationMay influence tumor microenvironment and cancer progression based on lncRNA family rolesOther (function still largely uncharacterized and likely context dependent)
03

Disease associations

Cancer (prognostic biomarker candidate in risk models for gastric cancer)Other (no confirmed role in non-cancer diseases yet)
04

Biomarkers

Prognostic biomarker for cancer risk stratification, notably gastric cancer

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