Target intelligence / Profile preview

Long intergenic non-protein coding RNA 3059 (LINC03059)

Target
LINC03059
Molecular classification
Long non-coding RNA (lncRNA)
01

Overview

Long intergenic non-protein coding RNA 3059 (LINC03059, also known as RP11-108M12.3) is a human gene encoding a long non-coding RNA molecule located at chromosome 14q22.3 (chr14:56,953,826-57,112,685)[3][7][9]. It is classified as a lncRNA, implying it does not code for a protein and functions primarily in gene regulation by modulating transcription, RNA stability, and chromatin structure[9][11]. LINC03059 has approved nomenclature according to HGNC (HGNC:56366)[1][9], and its RNA-based nature means it is not considered a canonical therapeutic target like receptors or enzymes. While long intergenic non-coding RNAs are increasingly recognized for roles in cell cycle regulation, apoptosis, immune response, and cancer biology, specific functional data for LINC03059, including its downstream biological pathways or disease associations, remain uncharacterized as of late 2025[11]. No drugs, biomarkers, or safety considerations have been formally attributed to this molecule.

Other names
RP11-108M12.3GC14U902722GC14M057064
02

Mechanism of action

Null. There are no known mechanisms of action for drugs targeting LINC03059

03

Biological functions

Regulatory functions at the transcriptional and post-transcriptional level (general for lincRNAs)Modulation of signaling pathways through interaction with other RNAs or chromatin (general for lincRNAs)
04

Disease associations

Other. While long intergenic non-coding RNAs (lincRNAs) like LINC03059 have been implicated in cancer, inflammation, and immune regulation, there is no specific published data directly tying LINC03059 to a well-defined disease role as of September 2025

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