Long intergenic non-protein coding RNA 351 (LINC00351)

LINC00351, or long intergenic non-protein coding RNA 351, is a human gene that generates a non-coding RNA transcript over 200 nucleotides in length. This type of RNA is not translated into a protein but instead plays diverse roles in regulating gene expression, chromatin remodeling, and maintaining genomic architecture. LINC00351 belongs to the class of long intergenic non-coding RNAs (lincRNAs), which often function in a tissue-specific manner to fine-tune neighboring gene activity through multiple mechanisms. Although lincRNAs as a group have been implicated in various cellular and disease processes, no validated, direct functional or disease-specific associations are currently reported for LINC00351[1][5][7][9][13][15]. There is no evidence that LINC00351 acts as a conventional therapeutic target (such as a receptor, enzyme, transporter, or transcription factor). It is also not commonly associated with biomarkers, specific drugs, or direct safety concerns; its classification is strictly as a long intergenic non-coding RNA, primarily involved in regulation at the RNA level.

Other names

LINC00351long intergenic non-protein coding RNA 351