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Long intergenic non-protein coding RNA 364 (LINC00364)
- Target
- LINC00364
- Molecular classification
- Other (specifically, long non-coding RNA)
01
Overview
Long intergenic non-protein coding RNA 364 (LINC00364) is a member of the long non-coding RNA (lncRNA) family. It is a non-protein coding RNA molecule transcribed from the human genome, with primary literature and database entries indicating its involvement in modulating cell proliferation, notably through the p-STAT3–IFIT2 signaling axis, thereby acting to repress proliferation in hepatocellular carcinoma. LINC00364 has also been denoted as LncRNA00364 in some sources but is distinct from protein-coding therapeutic targets such as receptors or enzymes. Current data do not indicate LINC00364 is directly druggable or targeted by therapeutics, nor is it widely established as a disease biomarker, although research into its role in cancer biology is ongoing.
- Other names
- LncRNA00364LNCRNA00364
02
Biological functions
Cell proliferationOther (regulation of gene expression—the mechanistic details are not fully clarified but related to signal axis modulation)
03
Disease associations
Cancer (notably hepatocellular carcinoma)Other (potential roles in additional cancers remain under investigation)
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