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Long intergenic non-protein coding RNA 383 (LINC00383) is a human gene encoding a long intergenic non-coding RNA, part of the lincRNA subclass of long non-coding RNAs. LINC00383 is autonomously transcribed from intergenic regions and does not encode a protein. While thousands of lincRNAs have been annotated, only a small proportion have well-defined functions. LincRNAs generally regulate gene expression through diverse mechanisms including chromatin remodeling, transcriptional regulation, and organization of nuclear architecture. For LINC00383 specifically, as for many annotated lincRNAs, there is currently no detailed characterization regarding its molecular function, biological role, or disease association in peer-reviewed databases or genomics resources. It remains a non-coding RNA gene with uncharacterized function, not classed as a therapeutic target at this time.
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