Long intergenic non-protein coding RNA 390 (LINC00390)

Long intergenic non-protein coding RNA 390 (LINC00390) is a long non-coding RNA (lncRNA) located on human chromosome 13, annotated with several aliases including TCONS_00021641, C13orf44, and SMIM2-IT1. LINC00390 does not code for a protein but is classified as an intergenic lncRNA, which are a class of RNA molecules transcribed from non-coding regions between genes. Like other lncRNAs, LINC00390 is presumed to play roles in the regulation of gene expression, chromatin structure, and RNA metabolism, potentially influencing nearby gene activity or acting within broader regulatory networks. Most lncRNAs, including LINC00390, do not have well-defined, molecule-specific biological or disease-related functions, and there is currently no published evidence linking LINC00390 specifically to human disease, drug targeting, or clinical biomarker applications. The biological importance of lncRNAs as a class is widely recognized, and their functions include fine-tuning gene expression, tissue-specific gene regulation, and contributing to genome architecture, but structural and mechanistic details for individual transcripts like LINC00390 are largely uncharacterized at present.

Other names

TCONS_00021641C13orf44SMIM2C13orf44-IT1C13orf44 intronic transcript 1 (non-protein coding)SMIM2 intronic transcript 1 (non-protein coding)SMIM2-IT1

Not applicable; no drugs documented to target this molecule