Target intelligence / Profile preview

Long intergenic non-protein coding RNA 437 (LINC00437)

Target
LINC00437
Molecular classification
Long non-coding RNA, Long intergenic non-coding RNA
01

Overview

LINC00437 (long intergenic non-protein coding RNA 437) is a human gene that encodes a long intergenic non-coding RNA (lincRNA), transcribed from chromosome 13q13, with the NCBI Gene accession 101929121[1][3][5][7]. LINC00437 belongs to the class of lncRNAs that do not overlap protein-coding genes and are generally transcribed as long RNAs (>200 nucleotides) without protein-coding potential[1][6]. LincRNAs such as LINC00437 commonly function in regulation of gene expression, chromatin remodeling, and related epigenetic or post-transcriptional mechanisms, and can act in cis (nearby) or trans (at distant loci), often in a tissue-specific manner[2][4][8]. While some lincRNAs have demonstrated disease associations and biomarker use, there is currently limited published functional or disease-related information specific to LINC00437. The gene is also referenced under the alias TCONS_00021639[5][7].

Other names
LINC00437TCONS_00021639
02

Biological functions

Regulation of gene expressionChromatin remodelingRNA stabilization and metabolismTranscriptional regulation

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