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Long intergenic non-protein coding RNA 471 (LINC00471)
- Target
- LINC00471
- Molecular classification
- Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01
Overview
Long intergenic non-protein coding RNA 471 (LINC00471) is a long non-coding RNA transcript that does not encode a protein and is located between protein-coding genes on chromosome 2. It is part of the lincRNA subclass of lncRNAs, defined by their lack of overlap with protein-coding loci. LINC00471’s biological functions are not fully characterized, consistent with many lncRNAs for which specific cellular or disease roles remain unclear. In general, lincRNAs can act in chromatin remodeling, regulation of transcription, and modulation of gene expression, often displaying tissue-specific expression profiles. The gene is well annotated and included in major genome databases.
- Other names
- C2ORF52MGC43122
02
Biological functions
Potential regulatory RNA (exact function unknown for this locus; lincRNAs are generally involved in chromatin remodeling, genome architecture, transcription regulation, and RNA stabilization)
03
Disease associations
No well-established direct role in disease for LINC00471; however, many lincRNAs are implicated in cancer and other diseases as regulatory molecules or biomarkers
04
Biomarkers
Not specifically reported for LINC00471; lncRNAs are broadly investigated as biomarkers for cancer, development, and other physiological states
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