Target intelligence / Profile preview

Long intergenic non-protein coding RNA 536 (LINC00536)

Target
LINC00536
Molecular classification
Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01

Overview

Long intergenic non-protein coding RNA 536 (LINC00536) is a long non-coding RNA classified as a lincRNA, meaning it is a transcript greater than 200 nucleotides that does not overlap protein-coding genes and is not translated into protein. LINC00536 has been reported to act as an oncogene in breast cancer, promoting cell proliferation, migration, and invasion. It is thought to influence cancer cell behavior and may serve as a potential biomarker for disease progression. LINC00536 does not encode a protein or function as a traditional druggable target such as an enzyme, receptor, or transporter; instead, it likely exerts regulatory roles at the transcriptional or epigenetic level as is common for lncRNAs. There are no known direct drug interactions or described mechanisms of pharmacological inhibition or activation for LINC00536.

Other names
LINC00536
02

Biological functions

Cell proliferationCell migrationCell invasionGene regulation
03

Disease associations

Cancer (notably breast cancer)
04

Biomarkers

Potential biomarker for breast cancer progression

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