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Long intergenic non-protein coding RNA 583 (LINC00583)

Target
LINC00583
Molecular classification
Other (Long intergenic non-coding RNA, lincRNA; classified as a type of long non-coding RNA)
01

Overview

Long intergenic non-protein coding RNA 583 (LINC00583) is a long intergenic non-coding RNA gene, meaning it is transcribed into a non-protein coding RNA molecule longer than 200 nucleotides and located in a genomic region that does not overlap with protein-coding genes[5][1]. LINC00583 belongs to the class of lincRNAs, which are distinguished from other non-coding RNAs by their length and genomic location. LincRNAs are recognized for their roles in chromatin remodeling, transcriptional regulation, and regulation of neighboring gene expression, often in a tissue- or context-specific manner, but only a small subset of annotated lincRNAs have been functionally characterized in detail[3][7]. There is currently no evidence that LINC00583 is a direct therapeutic target (such as a receptor, enzyme, transporter, etc.), nor are there established interacting drugs, biomarker roles, or documented safety concerns associated specifically with LINC00583[1][5].

Other names
C9orf146LINC00583
02

Biological functions

Chromatin remodelingTranscription regulationRNA stabilizationEnhancer-associated activity
03

Disease associations

Other (Potential tissue-specific roles in gene regulation and disease, but no established, direct role in specific diseases reported for LINC00583 itself)

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