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Target intelligence / Profile preview
long intergenic non-protein coding RNA 602 (LINC00602)
- Target
- LINC00602
- Molecular classification
- Long non-coding RNA (lncRNA), Intergenic RNA
01
Overview
long intergenic non-protein coding RNA 602 (LINC00602) encodes a long non-coding RNA located on chromosome 6, and is classified as an intergenic lncRNA with multiple transcript variants[1][3][7][9]. It does not encode a protein; rather, it functions in gene regulation, possibly through epigenetic mechanisms and modulation of transcriptional programs. Recent studies have implicated the methylation status of LINC00602 in influencing childhood lung development and lifelong susceptibility to asthma and COPD[5]. While LINC00602 is functionally associated with regulatory processes and potentially disease, it is not directly targeted by any known therapeutic agents and is not considered a classical drug target such as a receptor or enzyme[1][3][5][7][9].
- Other names
- LINC00602NR_027284.1AK094116.1
02
Biological functions
Regulation of gene expressionEpigenetic modulation (e.g., DNA methylation)Transcriptional regulation
03
Disease associations
Potential association with asthma and chronic obstructive pulmonary disease (COPD) via epigenetic changes and regulatory roles in lung functionReported differential methylation associated with childhood respiratory outcomesAssociations with cancer have not been clearly described for LINC00602 specifically in the retrieved literature, but other lncRNAs have established cancer roles
04
Biomarkers
DNA methylation status at LINC00602 locus may serve as a biomarker for pediatric lung function and risk of respiratory diseases (asthma and COPD)
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