Long intergenic non-protein coding RNA 635 (LINC00635)

LINC00635 is a long intergenic non-protein coding RNA gene, transcribed as a non-coding RNA longer than 200 nucleotides and does not overlap with annotated coding genes[1][3]. LINC00635 is primarily recognized for its elevated expression in serum exosomes of patients with hepatocellular carcinoma, where its levels are correlated with disease severity, including lymph node metastasis, TNM stage, and overall survival[2]. The combination of exosomal LINC00635 with other biomarkers (AFP, ENSG00000258332.1) may provide improved diagnostic and prognostic accuracy for HCC[2]. Like other lincRNAs, LINC00635 is anticipated to participate in gene regulation, chromatin dynamics, and possibly specific cellular or disease contexts, although its precise molecular and biological functions remain largely undefined. There is no evidence that LINC00635 is a conventional drug target, but its clinical significance in cancer biomarker discovery is emerging[1][2][3].

Other names

LINC00635ENSG00000258332.1