Long intergenic non-protein coding RNA 837 (LINC00837)

Long intergenic non-protein coding RNA 837 (LINC00837) is a human long non-coding RNA (lncRNA) gene, annotated as non-protein coding, generally not translated into protein. LINC00837 has been implicated in the regulation of cell proliferation, migration, and secretion of inflammatory factors, including through a functional axis involving miR-671-5p and SERPINE2 in rheumatoid arthritis fibroblast-like synoviocytes. There is emerging evidence of association with tumorigenic pathways, but as yet, it is neither a confirmed therapeutic target nor established as a clinical biomarker. LINC00837 is primarily classified within the family of long intergenic non-coding RNAs, with primary annotation as a regulatory RNA molecule rather than an enzyme, receptor, or transporter. LINC00837 is found on chromosome 10 in humans. LncRNAs like LINC00837 can modulate gene expression at epigenetic, transcriptional, and post-transcriptional levels, and while their clinical applications are under investigation, they are not yet translated into approved therapies. Note: There is no evidence that LINC00837 is misspelled or refers to an incorrect entity; however, its functional characterization is still in the research phase, and its use as a drug target, safety concern, or biomarker is not established in clinical practice.

Other names

LINC00837Long intergenic non-protein coding RNA 837NR_038374.1 (RefSeq transcript)ENSG00000235824 (Ensembl gene ID)