Long intergenic non-protein coding RNA 851 (LINC00851)

Long intergenic non-protein coding RNA 851 (LINC00851) is a human long intergenic non-coding RNA (lincRNA), meaning it is transcribed from the genome but does not encode a protein product[1][3]. As a member of the lincRNA family, LINC00851 is autonomously transcribed and is longer than 200 nucleotides, with its gene locus located in a region of the genome that does not overlap any annotated protein-coding genes[7]. While the precise biological roles and disease relevance of LINC00851 remain uncharacterized, lincRNAs are generally involved in the regulation of gene expression via multiple mechanisms, including chromatin remodeling, modulating transcription, stabilizing other RNAs, and potentially acting as enhancers[7]. There is no current evidence placing LINC00851 as a traditional drug target (such as a receptor, enzyme, or transporter), and no drugs, mechanisms of action, or biomarker uses are reported for this gene in the sources provided[1][3][5]. Note: DZANK1-AS1 indicates an antisense relationship to the protein-coding DZANK1 gene, but the two should not be confused; LINC00851 itself is not a protein and is distinct from the DZANK1 protein[1][3][6][8].

Other names

DZANK1-AS1DZANK1 antisense RNA 1 (non-protein coding)DZANK1 antisense RNA 1 (tail to tail)LINC00851