Long intergenic non-protein coding RNA 865 (LINC00865)

Long intergenic non-protein coding RNA 865 (LINC00865) is a long non-coding RNA (lncRNA) gene located on chromosome 10q23.31, spanning approximately 400,000 base pairs[1][3][5][7]. LINC00865 does not encode a protein but may play a regulatory role in gene expression and chromatin architecture, similar to other lncRNAs, and is primarily classified as an RNA gene of the lncRNA class[3][5][7]. LINC00865 has been weakly associated with glioma susceptibility, though there is little direct evidence linking it to disease-specific mechanisms or to use as a biomarker or therapeutic target[7][9]. No drugs or specific modulators have been reported to target LINC00865[7][9]. Its broader family, lncRNAs, are recognized to regulate gene expression at multiple levels, including chromatin modification, transcription, and post-transcriptional regulation[10]. Currently, LINC00865 itself is not considered a clinically actionable or therapeutic target.

Other names

LINC00865TCONS_00018278LINC01374hCG2024094Long intergenic non-protein coding RNA 1374