Long intergenic non-protein coding RNA 871 (LINC00871)

Long intergenic non-protein coding RNA 871 (LINC00871) is a non-coding RNA gene located on chromosome 14q21.2[3][7]. It is classified as a long non-coding RNA (lncRNA), meaning it does not encode a protein but may regulate gene expression through various mechanisms at the transcriptional or post-transcriptional level[9]. LINC00871 has been identified as functionally relevant in diverse biological processes, including regulation of immune microenvironment, differentiation of T helper cells, immune exclusion in tumors, and association with prognosis in cancers such as breast cancer and colon cancer[4][8][10]. It is frequently considered in signatures for prognostic models rather than as a direct molecular target for drug therapy, and there are no known drugs that directly interact with or modulate LINC00871[4][8]. Its biological effects are attributed to its role in gene regulatory networks and immune modulation, rather than serving as a receptor, enzyme, or transporter.

Other names

RP11-1A16.1LINC00871

Not applicable; no drugs are known to target LINC00871 directly