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Target intelligence / Profile preview
Long intergenic non-protein coding RNA 877 (LINC00877)
- Target
- LINC00877
- Molecular classification
- Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01
Overview
LINC00877 (long intergenic non-protein coding RNA 877) is a member of the lincRNA family located on chromosome 3 at 3p13 (71,943,592-72,279,946, reverse strand). LincRNAs are defined as non-coding RNA transcripts longer than 200 nucleotides, originating from intergenic regions of the genome and involved in tissue-specific gene regulation. The specific biological function, regulatory mechanism, and disease association of LINC00877 remain uncharacterized in the literature. It is catalogued in several transcriptomic and genomics resources (HGNC, Ensembl, NCBI, GeneCards) and serves as an example of the thousands of annotated human lincRNAs whose functional roles are still being investigated.
- Other names
- LINC00877Long intergenic non-protein coding RNA 877HGNC:27706NCBI Gene:285286Ensembl:ENSG00000241163GeneCards previous IDs: GC03M072086GeneCards previous IDs: GC03M072036GeneCards previous IDs: GC03M071943
02
Mechanism of action
Not applicable; no drugs are known to target LINC00877.
03
Biological functions
Unknown for LINC00877Regulation of gene expression at multiple levels (general lincRNA function)Chromatin and genome architecture remodeling (general lincRNA function)Stabilization or interaction with RNAs/proteins (general lincRNA function)Potential enhancer-like regulatory function (general lincRNA function)
04
Disease associations
No well-established direct disease roles for LINC00877General lncRNAs are implicated in various diseases such as cancer, immune disorders, and neurological disease
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