Long intergenic non-protein coding RNA 893 (LINC00893)

Long intergenic non-protein coding RNA 893 (LINC00893), also known as EOLA1 divergent transcript (EOLA1-DT), is a member of the long non-coding RNA (lncRNA) class. These transcripts are over 200 nucleotides in length and do not code for proteins, but can regulate gene expression locally or at a distance in the genome[2]. Divergent lncRNAs are transcribed in close genomic proximity and in the opposite direction to adjacent protein-coding genes, often participating in transcriptional and epigenetic regulation[1]. The alias "CRC progression-associated lncRNA" suggests that LINC00893/EOLA1-DT may be involved in colorectal cancer, although its biological role, mechanisms, and potential as a biomarker or target remain largely uncharacterized in current literature. No drugs, direct mechanisms of action, or safety issues have been documented for this target[2][3].

Other names

EOLA1 divergent transcriptLINC00893lnc-CPLCgene WCRC progression-associated lncRNALong intergenic non-protein coding RNA 893