Long intergenic non-protein coding RNA 910 (LINC00910)

Long intergenic non-protein coding RNA 910 (LINC00910) is a long non-coding RNA gene on human chromosome 19, although some sources reference it on chromosome 17, most databases support chromosome 19[3][5]. It does not encode a protein, but like other lincRNAs, it acts as a versatile regulator of gene expression at several molecular levels. LINC00910 can participate in both promoter-like and enhancer-like chromatin interactions, bridging distant DNA loci, altering local chromatin environments, and thereby impacting transcriptional regulation[1][2]. It also influences alternative splicing and gene expression in a cell type-specific manner, likely serving as a scaffold for protein-RNA and nucleic acid interactions. LINC00910 has been found to be differentially expressed in multiple cancers (breast, gastric, lung, osteosarcoma), where it may act as a prognostic marker and may drive tumorigenesis or suppress tumors depending on the context[3][5]. Although its precise molecular mechanisms and broader clinical significance remain under investigation, current evidence points to a key regulatory role in gene networks related to cancer and possibly other diseases, such as polycystic ovary syndrome[1][3][5]. No direct drug interactions, mechanisms of action for drugs, or safety concerns have been reported. LINC00910 is not considered a classical therapeutic target such as a receptor, enzyme, or transporter.

Other names

CTD-3014M21.4LINC00910