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Long intergenic non-protein coding RNA 937 (LINC00937)
- Target
- LINC00937
- Molecular classification
- Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01
Overview
LINC00937 (Long intergenic non-protein coding RNA 937) is a member of the long intergenic non-coding RNA (lincRNA) family, a subclass of long non-coding RNAs (>200 nucleotides) that do not code for proteins and are located between coding genes in the genome. The precise biological function of LINC00937 is not well characterized, but lincRNAs overall are known to play roles in gene expression regulation, chromatin remodeling, and possibly epigenetic modifications. They can regulate genes nearby (cis) or at a distance (trans), and growing evidence suggests some are differentially expressed in cancer and may have potential as diagnostic or prognostic biomarkers. LINC00937 itself does not encode a protein, is not recognized as a classical therapeutic target, and as of current literature, has no known interacting drugs or direct disease-modifying actions.
- Other names
- LINC00937
02
Mechanism of action
None established for drugs (as LINC00937 is not a protein target and no drugs are known to directly modulate it)
03
Biological functions
Gene regulationChromatin modificationRNA metabolismTranscriptional regulation
04
Disease associations
Cancer
05
Safety considerations
None specific to LINC00937Poor understanding of off-target effects of lncRNA targetingChallenges in delivery mechanisms for lncRNA targetingFunctional redundancy in lncRNA targeting
06
Biomarkers
Molecular biomarkers for cancer
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