Long intergenic non-protein coding RNA 938 (LINC00938)

Long intergenic non-protein coding RNA 938 (LINC00938) is a human long non-coding RNA (lncRNA) gene located on chromosome 8 and does not code for a protein[1][5][6]. It is classified as an intergenic lncRNA and has been implicated through bioinformatic analyses in biological processes including gene regulation, cilium morphogenesis, and skin development[3][4]. LINC00938 is downregulated in breast cancer tissues and identified as a possible tumor suppressor lncRNA[2]. It is also suggested to serve as a biomarker for prognosis in both breast cancer and non-small cell lung cancer, based on expression signatures, but its precise molecular mechanism remains to be experimentally validated[2][4]. There are currently no known drugs targeting it directly, and its therapeutic relevance is limited to its investigational role as a biomarker rather than a proven actionable target[2][4].