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Long intergenic non-protein coding RNA 94 (LINC00094)

Target
LINC00094
Molecular classification
Other (Long intergenic non-coding RNA; lincRNA)
01

Overview

BRD3OS (LINC00094), also known as Long intergenic non-protein coding RNA 94, is a long intergenic non-coding RNA (lincRNA), meaning it is a non-protein-coding transcript longer than 200 nucleotides that does not overlap protein-coding regions[2]. It is also referred to by several aliases, including BRD3 opposite strand, Non-protein coding RNA 94, and SERLOC. BRD3OS has been described as "Super enhancer and ERK1/2 Regulated Long Intergenic non-protein coding transcript Overexpressed in Carcinomas," reflecting its overexpression in certain cancer types and potential involvement in enhancer-like activity and transcriptional regulation[2]. While its precise biological and disease functions are not fully characterized, lincRNAs like BRD3OS are recognized for their broad roles in fine-tuning gene expression, chromatin and genome architecture, and possibly RNA stabilization. There are currently no approved drugs or established therapeutic approaches that directly target BRD3OS, nor are there validated biomarkers or safety concerns specific to this RNA molecule. Its functional and disease associations remain under investigation.

Other names
BRD3 opposite strandBRD3OSNon-protein coding RNA 94NCRNA00094FLJ35348bA374P20.3SERLOCBRD3 opposite strand proteinUncharacterized protein BRD3OSSuper enhancer and ERK1/2 Regulated Long Intergenic non-protein coding transcript Overexpressed in CarcinomasLP2477
02

Biological functions

Regulation of gene expressionChromatin remodelingTranscription regulationPotential enhancer-associated activityRNA stabilization
03

Disease associations

Cancer (overexpressed in carcinomas)Other (under research)

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