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Louse Metalloproteinase

Molecular classification: Enzyme, Metalloproteinase

Overview

Louse metalloproteinases are a class of enzymes produced by lice (such as Pediculus humanus capitis, the head louse) that play essential roles in the development and reproductive cycle of these ectoparasites. These enzymes belong to the broader family of metalloproteinases, which require metal ions (typically zinc) for their catalytic activity. They are critical for egg hatching and tissue remodeling. Abametapir is a known inhibitor.

Mechanism of action

Inhibition of metalloproteinase activity via metal ion chelation

Biological functions

Egg hatchingTissue remodelingDevelopment

Disease associations

Infection

Interacting drugs

Abametapir

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