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Target intelligence / Profile preview
Low-molecular-weight chromium-binding substance (LMWCr (chromodulin))
- Target
- LMWCr (chromodulin)
- Molecular classification
- Other, Metallopeptide
01
Overview
Low-molecular-weight chromium-binding substance (chromodulin) is a small oligopeptide that binds chromium ions and regulates insulin receptor activity, with unclear structure and mechanism, not a conventional therapeutic target[1][2][3][4][5][6][7].
- Other names
- chromodulinLMWCrlow-molecular-weight chromium-binding peptidelow-molecular-weight chromium-binding substance
02
Mechanism of action
Potentiates insulin receptor activity; Facilitates tissue chromium uptake
03
Biological functions
Insulin signaling modulationGlucose metabolism regulationChromium transport
04
Disease associations
DiabetesOther (potentially metabolic syndrome)
05
Safety considerations
None specific to chromodulin; chromium supplementation safety debated
06
Interacting drugs
None established
07
Biomarkers
None established
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